Transcriptional profiling of aging in human muscle reveals a common aging signature.

We analyzed expression of 81 normal muscle samples from humans of varying ages, and have identified a molecular profile for aging consisting of 250 age-regulated genes. This molecular profile correlates not only with chronological age but also with a measure of physiological age. We compared the tra...

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Bibliographic Details
Main Authors: Jacob M Zahn, Rebecca Sonu, Hannes Vogel, Emily Crane, Krystyna Mazan-Mamczarz, Ralph Rabkin, Ronald W Davis, Kevin G Becker, Art B Owen, Stuart K Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1513263?pdf=render