CSE/H2S system alleviates uremic accelerated atherosclerosis by regulating TGF-β/Smad3 pathway in 5/6 nephrectomy ApoE−/− mice

Abstract Background Hydrogen sulfide (H2S) has been shown to inhibit the atherosclerosis development and progression. It is produced by cystathionine γ-lyase (CSE) in the cardiovascular system. In our previous study, it has been shown that CSE/H2S system plays a significant role in the changes of ur...

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Bibliographic Details
Main Authors: Xiangxue Lu, Shixiang Wang, Sujuan Feng, Han Li
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Nephrology
Subjects:
Online Access:https://doi.org/10.1186/s12882-020-02183-z