Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model

Combining different types of immune therapies might benefit certain patients. Here, the authors develop an autologous immune-humanized melanoma mouse model that allows the preclinical assessment of cancer cell–T cell interactions from each individual patient and the benefits of immunotherapies combi...

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Bibliographic Details
Main Authors: Henrik Jespersen, Mattias F. Lindberg, Marco Donia, Elin M. V. Söderberg, Rikke Andersen, Ulrich Keller, Lars Ny, Inge Marie Svane, Lisa M. Nilsson, Jonas A. Nilsson
Format: Article
Language:English
Published: Nature Publishing Group 2017-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00786-z