Acute Myelogenous Leukemia without Maturation with a Retinoic Alpha-Receptor Deletion: A Case Report

Acute promyelocytic leukemia (APL) is characterized by a t(15;17) which fuses the 17q retinoic acid alpha-receptor sequence to the 15q PML gene sequence. The resulting fusion product plays a role in the development and maintenance of APL, and is very rarely found in other acute myeloid leukemia (AML...

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Bibliographic Details
Main Authors: Christopher Trosclair, Maressa Pollen, Gerald Capraro, James Cotelingam, Rodney E. Shackelford
Format: Article
Language:English
Published: Karger Publishers 2014-06-01
Series:Case Reports in Oncology
Subjects:
Online Access:http://www.karger.com/Article/FullText/365002