Disruption of the BMEI0066 gene attenuates the virulence of Brucella melitensis and decreases its stress tolerance

<p><i>Brucella melitensis</i> is a facultative intracellular pathogen. An operon composed of BMEI0066, which encodes a two-component response regulator CenR, and BMEI0067, which encodes a cAMP-dependent protein kinase regulatory subunit, has been predicted to exist in many bacteria...

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Bibliographic Details
Main Author: Xinglin Zhang, Jie Ren, Na Li, Wenjuan Liu, Qingmin Wu
Format: Article
Language:English
Published: Ivyspring International Publisher 2009-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v05p0570.htm