The crystal structure of D-threonine aldolase from Alcaligenes xylosoxidans provides insight into a metal ion assisted PLP-dependent mechanism.

The crystal structure of D-threonine aldolase from Alcaligenes xylosoxidans provides insight into a metal ion assisted PLP-dependent mechanism.

Threonine aldolases catalyze the pyridoxal phosphate (PLP) dependent cleavage of threonine into glycine and acetaldehyde and play a major role in the degradation of this amino acid. In nature, L- as well as D-specific enzymes have been identified, but the exact physiological function of D-threonine...

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Bibliographic Details
Main Authors: Michael K Uhl, Gustav Oberdorfer, Georg Steinkellner, Lina Riegler-Berket, Daniel Mink, Friso van Assema, Martin Schürmann, Karl Gruber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4401734?pdf=render

Internet

http://europepmc.org/articles/PMC4401734?pdf=render

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