LOXL2 attenuates osteoarthritis through inactivating Integrin/FAK signaling

Abstract Temporomandibular joint OA (TMJOA) is a common degenerative joint disease, leads to structural damage and ultimately loss of function. Matrix degradation is one of the first pathogenesis during the progression of OA, it was effective to inhibit matrix degradation to block the development of...

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Bibliographic Details
Main Authors: Caixia Zhang, Mengjiao Zhu, Huijuan Wang, Juan Wen, Ziwei Huang, Sheng Chen, Hongting Zhao, Huang Li
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96348-x