Non-BRAF Mutant Melanoma: Molecular Features and Therapeutical Implications

Non-BRAF Mutant Melanoma: Molecular Features and Therapeutical Implications

Melanoma is one of the most aggressive tumors of the skin, and its incidence is growing worldwide. Historically considered a drug resistant disease, since 2011 the therapeutic landscape of melanoma has radically changed. Indeed, the improved knowledge of the immune system and its interactions with t...

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Bibliographic Details
Main Authors: Irene Vanni, Enrica Teresa Tanda, Bruna Dalmasso, Lorenza Pastorino, Virginia Andreotti, William Bruno, Andrea Boutros, Francesco Spagnolo, Paola Ghiorzo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
melanoma
non-BRAF mutation
targeted therapy
driver mutations
genetic
heterogeneity
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2020.00172/full

Internet

https://www.frontiersin.org/article/10.3389/fmolb.2020.00172/full

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