Clinical Metabolomics Identifies Blood Serum Branched Chain Amino Acids as Potential Predictive Biomarkers for Chronic Graft vs. Host Disease

Clinical Metabolomics Identifies Blood Serum Branched Chain Amino Acids as Potential Predictive Biomarkers for Chronic Graft vs. Host Disease

The allogeneic hematopoietic stem cell transplantation procedure—the only curative therapy for many types of hematological cancers—is increasing, and graft vs. host disease (GVHD) is the main cause of morbidity and mortality after transplantation. Currently, GVHD diagnosis is clinically performed. W...

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Bibliographic Details
Main Authors: Marcos Rodrigo Alborghetti, Maria Elvira Pizzigatti Correa, Jennifer Whangbo, Xu Shi, Juliana Aparecida Aricetti, Andreia Aparecida da Silva, Eliana Cristina Martins Miranda, Mauricio Luis Sforca, Camila Caldana, Robert E. Gerszten, Jerome Ritz, Ana Carolina de Mattos Zeri
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Oncology
Subjects:
graft vs. host disease
bone marrow transplantation
cancer
metabolomics
branched chain amino acids
biomarkers
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00141/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00141/full

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