Deficiency in IL-33/ST2 Axis Reshapes Mitochondrial Metabolism in Lipopolysaccharide-Stimulated Macrophages

The polarization and function of macrophages play essential roles in controlling immune responses. Interleukin (IL)-33 is a member of the IL-1 family that has been shown to influence macrophage activation and polarization, but the underlying mechanisms are not fully understood. Mitochondrial metabol...

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Bibliographic Details
Main Authors: Huadan Xu, Liankun Sun, Yichun He, Xiaofeng Yuan, Junqi Niu, Jing Su, Dong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
ST2
ATP
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00127/full