Exploration of structural stability in deleterious nsSNPs of the XPA gene: A molecular dynamics approach

Exploration of structural stability in deleterious nsSNPs of the XPA gene: A molecular dynamics approach

Background: Distinguishing the deleterious from the massive number of non-functional nsSNPs that occur within a single genome is a considerable challenge in mutation research. In this approach, we have used the existing in silico methods to explore the mutation-structure-function relationship in the...

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Bibliographic Details
Main Authors: N NagaSundaram, C George Priya Doss
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Journal of Carcinogenesis
Subjects:
I-Mutant
molecular dynamics
PANTHER
polyphen
SIFT
XPA
Online Access:http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2011;volume=10;issue=1;spage=26;epage=26;aulast=NagaSundaram

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http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2011;volume=10;issue=1;spage=26;epage=26;aulast=NagaSundaram

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