COVID-19 virtual patient cohort suggests immune mechanisms driving disease outcomes.

COVID-19 virtual patient cohort suggests immune mechanisms driving disease outcomes.

To understand the diversity of immune responses to SARS-CoV-2 and distinguish features that predispose individuals to severe COVID-19, we developed a mechanistic, within-host mathematical model and virtual patient cohort. Our results suggest that virtual patients with low production rates of infecte...

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Bibliographic Details
Main Authors: Adrianne L Jenner, Rosemary A Aogo, Sofia Alfonso, Vivienne Crowe, Xiaoyan Deng, Amanda P Smith, Penelope A Morel, Courtney L Davis, Amber M Smith, Morgan Craig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009753

Internet

https://doi.org/10.1371/journal.ppat.1009753

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