Confirmation of GLRA3 as a susceptibility locus for albuminuria in Finnish patients with type 1 diabetes

Abstract Urinary albumin excretion is an early sign of diabetic kidney disease, affecting every third individual with diabetes. Despite substantial estimated heritability, only variants in the GLRA3 gene have been genome-wide significantly associated (p-value < 5 × 10−8) with diabetic albuminuria...

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Bibliographic Details
Main Authors: Niina Sandholm, Jani K Haukka, Iiro Toppila, Erkka Valo, Valma Harjutsalo, Carol Forsblom, Per-Henrik Groop
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-29211-1