Anticancer effects of 7,8-dihydromethysticin in human leukemia cells are mediated via cell-cycle dysregulation, inhibition of cell migration and invasion and targeting JAK/STAT pathway

The main focus of this research work was to study the anti-cancer properties of 7,8-dihydromethysticin against HL-60 leukemia cells. Investigations were also performed to check its impact on the phases of the cell cycle, cell migration and invasion, JAK/STAT signalling pathway and intracellular mito...

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Bibliographic Details
Main Authors: Xiao Yi, Deng Taoran, Jiang Lijun, Wang Di
Format: Article
Language:English
Published: Sciendo 2021-12-01
Series:Acta Pharmaceutica
Subjects:
7
Online Access:https://doi.org/10.2478/acph-2021-0037