Protective Effects of Peroxiredoxin 4 (PRDX4) on Cholestatic Liver Injury

Protective Effects of Peroxiredoxin 4 (PRDX4) on Cholestatic Liver Injury

Accumulating evidence indicates that oxidative stress plays a critical role in initiating the progression of inflammatory and fibrotic liver diseases, including cholestatic hepatitis. Peroxiredoxin 4 (PRDX4) is a secretory antioxidase that protects against oxidative damage by scavenging reactive oxy...

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Bibliographic Details
Main Authors: Jing Zhang, Xin Guo, Taiji Hamada, Seiya Yokoyama, Yuka Nakamura, Jianbo Zheng, Nozomu Kurose, Yasuhito Ishigaki, Hidetaka Uramoto, Akihide Tanimoto, Sohsuke Yamada
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
PRDX4
liver injury
oxidative stress
cholestasis
BDL
Online Access:http://www.mdpi.com/1422-0067/19/9/2509

Internet

http://www.mdpi.com/1422-0067/19/9/2509

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