A combined tissue‐engineered/in silico signature tool patient stratification in lung cancer

Patient‐tailored therapy based on tumor drivers is promising for lung cancer treatment. For this, we combined in vitro tissue models with in silico analyses. Using individual cell lines with specific mutations, we demonstrate a generic and rapid stratification pipeline for targeted tumor therapy. We...

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Bibliographic Details
Main Authors: Claudia Göttlich, Meik Kunz, Cornelia Zapp, Sarah L. Nietzer, Heike Walles, Thomas Dandekar, Gudrun Dandekar
Format: Article
Language:English
Published: Wiley 2018-08-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1002/1878-0261.12323