Impact of the manufacturing technique on the dissolution-enhancement functionality of PEG4000 in Cilostazol tablets
Cilostazol was selected as poorly-soluble model drug to investigate the impact of the manufacturing method on the excipient functionality of PEG4000 at various levels. Powder blends were prepared by direct compression (DC), wet granulation (WG) and hot-melt extrusion (HME). Character...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Pensoft Publishers
2021-02-01
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| Series: | Pharmacia |
| Online Access: | https://pharmacia.pensoft.net/article/62465/download/pdf/ |