The N-Terminal Domain of Y-Box Binding Protein-1 Induces Cell Cycle Arrest in G2/M Phase by Binding to Cyclin D1

Y-box binding protein YB-1 is a multifunctional protein involved in cell proliferation, regulation of transcription and translation. Our previous study indicated that disruption of one allele of Chk-YB-1b gene in DT-40 cells resulted in major defects in the cell cycle. The abnormalities seen in hete...

Full description

Bibliographic Details
Main Authors: Payal Khandelwal, Mythili K. Padala, John Cox, Ramareddy V. Guntaka
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2009/243532