Novel Cyclic Lipopeptide Antibiotics: Effects of Acyl Chain Length and Position

Multidrug-resistant bacteria are a global health problem. One of the last-resort antibiotics against Gram-negative bacteria is the cyclic lipopeptide colistin, displaying a flexible linker with a fatty acid moiety. The aim of the present project was to investigate the effect on antimicrobial activit...

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Bibliographic Details
Main Authors: Signe Kaustrup Jensen, Thomas T. Thomsen, Alberto Oddo, Henrik Franzyk, Anders Løbner-Olesen, Paul R. Hansen
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/16/5829