Prevalence and Spectrum of <i>BRCA</i> Germline Variants in Central Italian High Risk or Familial Breast/Ovarian Cancer Patients: A Monocentric Study

Prevalence and Spectrum of <i>BRCA</i> Germline Variants in Central Italian High Risk or Familial Breast/Ovarian Cancer Patients: A Monocentric Study

Hereditary breast and ovarian cancers are mainly linked to variants in <i>BRCA1</i>/2 genes. Recently, data has shown that identification of <i>BRCA</i> variants has an immediate impact not only in cancer prevention but also in targeted therapeutic approaches. This prospectiv...

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Bibliographic Details
Main Authors: Jennifer Foglietta, Vienna Ludovini, Fortunato Bianconi, Lorenza Pistola, Maria Sole Reda, Antonella Al-Refaie, Francesca Romana Tofanetti, Annamaria Mosconi, Elisa Minenza, Paola Anastasi, Carmen Molica, Fabrizio Stracci, Fausto Roila
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Genes
Subjects:
<i>BRCA1/2</i> variant carrier
breast cancer
VUS
genetic testing
risk evaluation
Online Access:https://www.mdpi.com/2073-4425/11/8/925

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https://www.mdpi.com/2073-4425/11/8/925

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