Altered theca and cumulus oocyte complex gene expression, follicular arrest and reduced fertility in cows with dominant follicle follicular fluid androgen excess.

Aspiration of bovine follicles 12-36 hours after induced corpus luteum lysis serendipitously identified two populations of cows, one with High androstenedione (A4; >40 ng/ml; mean = 102) and another with Low A4 (<20 ng/ml; mean = 9) in follicular fluid. We hypothesized that the steroid excess...

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Bibliographic Details
Main Authors: Adam F Summers, William E Pohlmeier, Kevin M Sargent, Brizett D Cole, Rebecca J Vinton, Scott G Kurz, Renee M McFee, Robert A Cushman, Andrea S Cupp, Jennifer R Wood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4199720?pdf=render