Pentaisomaltose, an Alternative to DMSO. Engraftment of Cryopreserved Human CD34 Cells in Immunodeficient NSG Mice

Pentaisomaltose, an Alternative to DMSO. Engraftment of Cryopreserved Human CD34 Cells in Immunodeficient NSG Mice

Hematopoietic stem cell transplantation often involves the cryopreservation of stem cell products. Currently, the standard cryoprotective agent (CPA) is dimethyl sulfoxide (DMSO), which is known to cause concentration-related toxicity and side effects when administered to patients. Based on promisin...

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Bibliographic Details
Main Authors: Jesper Dyrendom Svalgaard, Mehrnaz Safaee Talkhoncheh, Eva Kannik Haastrup, Lea Munthe-Fog, Christian Clausen, Morten Bagge Hansen, Pernille Andersen, Jette Sønderskov Gørløv, Jonas Larsson, Anne Fischer-Nielsen
Format: Article
Language:English
Published: SAGE Publishing 2018-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689718786226

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https://doi.org/10.1177/0963689718786226

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