Synthesis, Antitumor Activity, and Docking Analysis of New Pyrido[3′,2′:4,5]furo(thieno)[3,2-<i>d</i>]pyrimidin-8-amines

Synthesis, Antitumor Activity, and Docking Analysis of New Pyrido[3′,2′:4,5]furo(thieno)[3,2-<i>d</i>]pyrimidin-8-amines

Continuing our research in the field of new heterocyclic compounds, herein we report on the synthesis and antitumor activity of new amino derivatives of pyrido[3&#8242;,2&#8242;:4,5](furo)thieno[3,2-<i>d</i>]pyrimidines as well as of two new heterocyclic systems: furo[2&#8722...

Full description

Bibliographic Details
Main Authors: Samvel N. Sirakanyan, Domenico Spinelli, Athina Geronikaki, Elmira K. Hakobyan, Harutyun Sahakyan, Erik Arabyan, Hovakim Zakaryan, Lusine E. Nersesyan, Anahit S. Aharonyan, Irina S. Danielyan, Rafayel E. Muradyan, Anush A. Hovakimyan
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
pyrido[3′,2′:4,5]furo(thieno)[3,2-<i>d</i>]pyrimidin-8-amines
amination
furo[2,3-<i>e</i>]imidazo[1,2-<i>c</i>]pyrimidine
furo[2,3-<i>e</i>]pyrimido[1,2-<i>c</i>]pyrimidine
dna methylation
sarcoma 180
antitumor activity
Online Access:https://www.mdpi.com/1420-3049/24/21/3952

Internet

https://www.mdpi.com/1420-3049/24/21/3952

Similar Items