CREKA peptide-modified docetaxel loaded liposomes for targeted treatment of prostate cancer in vitro

Objective To prepare CREKA peptide-modified docetaxel (DTX) loaded liposomes (CREKA-lipo-DTX) and to evaluate their targeted binding ability and anti-proliferative activity in vitro. Methods Firstly, Michael addition reaction was used to synthesize the targeted part DSPE-PEG2000-CREKA, and then CREK...

Full description

Bibliographic Details
Main Authors: YANG Wenbo, HAO Lan, WANG Zhigang2, ZHANG Ronggui
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2020-11-01
Series:Di-san junyi daxue xuebao
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202005276.htm