Alveolar Macrophage Dysfunction and Increased PD-1 Expression During Chronic SIV Infection of Rhesus Macaques

HIV infected individuals have been shown to be pre-disposed to pulmonary infections even while receiving anti-retroviral therapy. Alveolar macrophages (AMs) play a critical role in lung innate immunity, but contradictory results have been reported regarding their functionality following HIV infectio...

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Bibliographic Details
Main Authors: Ruth Hunegnaw, Zuena Mushtaq, Gospel Enyindah-Asonye, Tanya Hoang, Marjorie Robert-Guroff
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
SIV
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01537/full