Dexmedetomidine post-conditioning attenuates cerebral ischemia following asphyxia cardiac arrest through down-regulation of apoptosis and neuroinflammation in rats

Dexmedetomidine post-conditioning attenuates cerebral ischemia following asphyxia cardiac arrest through down-regulation of apoptosis and neuroinflammation in rats

Abstract Background Neuroprotection strategies after cardiac arrest (CA)/cardiopulmonary resuscitation (CPR) remain key areas of basic and clinical research. This study was designed to investigate the neuroprotective effects of dexmedetomidine following resuscitation and potential mechanisms. Method...

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Bibliographic Details
Main Authors: Guangqian Li, LeiQian, Pan Gu, Dan Fan
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Anesthesiology
Subjects:
Dexmedetomidine
Post-conditioning
Cerebral ischemia
Asphyxiacardiac arrest
Apoptosis
Neuroinflammation
Online Access:https://doi.org/10.1186/s12871-021-01394-7

Internet

https://doi.org/10.1186/s12871-021-01394-7

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