Chromosomal integration of aldo-keto-reductase and short-chain dehydrogenase/reductase genes in Clostridium beijerinckii NCIMB 8052 enhanced tolerance to lignocellulose-derived microbial inhibitory compounds

Abstract In situ detoxification of lignocellulose-derived microbial inhibitory compounds is an economical strategy for the fermentation of lignocellulose-derived sugars to fuels and chemicals. In this study, we investigated homologous integration and constitutive expression of Cbei_3974 and Cbei_390...

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Bibliographic Details
Main Authors: Christopher Chukwudi Okonkwo, Victor Ujor, Thaddeus Chukwuemeka Ezeji
Format: Article
Language:English
Published: Nature Publishing Group 2019-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-44061-1