Beyond EGFR Targeting in SCCHN: Angiogenesis, PI3K, and Other Molecular Targets

Although the molecular landscape of squamous cell carcinoma of the head and neck (SCCHN) has been largely deciphered, only one targeted therapy has been approved to date without any molecular selection, namely cetuximab. Cetuximab is a monoclonal antibody targeting EGFR. It has been shown to improve...

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Bibliographic Details
Main Authors: Esma Saada-Bouzid, Christophe Le Tourneau
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Oncology
Subjects:
HPV
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00074/full