Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity

Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity

Insulin and IGF signaling (IIS) is a complex system that controls diverse processes including growth, development, metabolism, stress responses, and aging. Drosophila melanogaster IIS is propagated by eight Drosophila insulin-like peptides (DILPs), homologs of both mammalian insulin and IGFs, with v...

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Bibliographic Details
Main Authors: Stephanie Post, Galina Karashchuk, John D. Wade, Waseem Sajid, Pierre De Meyts, Marc Tatar
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Endocrinology
Subjects:
insulin
IGF
Drosophila insulin-like peptides
glycogen phosphorylase
glycogen
metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00245/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00245/full

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