Region specific up-regulation of oxytocin receptors in the opioid Oprm1-/- mouse model of autism

Region specific up-regulation of oxytocin receptors in the opioid Oprm1-/- mouse model of autism

Autism spectrum disorders (ASDs) are characterized by impaired communication, social impairments and restricted and repetitive behaviors and interests. Recently altered motivation and reward processes have been suggested to participate in the physiopathology of ASDs, and μ-opioid receptors (MORs) ha...

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Bibliographic Details
Main Authors: Valentina eGigliucci, Marianna eLeonzino, Marta eBusnelli, Viola Stella Palladino, Alessandra eLuchetti, Francesca R D'Amato, Bice eChini
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Pediatrics
Subjects:
Social Behavior
autism
mu-opioid receptor
oxytocin receptor
ultrasonic vocalizations
brain autoradiography
Online Access:http://journal.frontiersin.org/Journal/10.3389/fped.2014.00091/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fped.2014.00091/full

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