Impaired long-term spatial and recognition memory and enhanced CA1 hippocampal LTP in the dystrophin-deficient Dmdmdx mouse

Impaired long-term spatial and recognition memory and enhanced CA1 hippocampal LTP in the dystrophin-deficient Dmdmdx mouse

Duchenne muscular dystrophy (DMD) is associated with cognitive deficits that may result from dystrophin deficiency in neurons. However, in the dystrophin-deficient Dmdmdx mouse model of DMD, the nature of the memory impairment is not well characterised and its biological substrate is uncertain. Here...

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Bibliographic Details
Main Authors: Cyrille Vaillend, Jean-Marie Billard, Serge Laroche
Format: Article
Language:English
Published: Elsevier 2004-10-01
Series:Neurobiology of Disease
Subjects:
Duchenne muscular dystrophy
Cognitive impairment
Spatial learning
Water maze
Object recognition
Mutant mice
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104001226

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http://www.sciencedirect.com/science/article/pii/S0969996104001226

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