Mechanism research of miR‐34a regulates Axl in non‐small‐cell lung cancer with gefitinib‐acquired resistance

Background To investigate the regulatory mechanism behind miR‐34a‐altered Axl levels in non‐small‐cell lung cancer (NSCLC) with gefitinib‐acquired resistance. Methods The expression of miR‐34a, Axl, Gas6 and related downstream signaling proteins in the EGFR mutant NSCLC cell lines were determined by...

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Bibliographic Details
Main Authors: Ran Xiong, Xiang‐xiang Sun, Han‐ran Wu, Guang‐wen Xu, Gao‐xiang Wang, Xiao‐hui Sun, Mei‐qing Xu, Ming‐ran Xie
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Thoracic Cancer
Subjects:
Online Access:https://doi.org/10.1111/1759-7714.13258