HSPCs display within-family homogeneity in differentiation and proliferation despite population heterogeneity

HSPCs display within-family homogeneity in differentiation and proliferation despite population heterogeneity

High-throughput single-cell methods have uncovered substantial heterogeneity in the pool of hematopoietic stem and progenitor cells (HSPCs), but how much instruction is inherited by offspring from their heterogeneous ancestors remains unanswered. Using a method that enables simultaneous determinatio...

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Bibliographic Details
Main Authors: Tamar Tak, Giulio Prevedello, Gaël Simon, Noémie Paillon, Camélia Benlabiod, Caroline Marty, Isabelle Plo, Ken R Duffy, Leïla Perié
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
haematopoietic stem
progenitor cell
concordance
cell differentiation
cell proliferation
Online Access:https://elifesciences.org/articles/60624

Internet

https://elifesciences.org/articles/60624

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