Metabolomics of Clinical Poisoning by Aconitum Alkaloids Using Derivatization LC-MS

The root of Aconitum kusnezoffii (Caowu in Chinese, CW) is not only commonly used as a traditional Chinese medicine (TCM), but also served as a tonic in China. Due to its high toxicity, clinical poisoning cases induced by CW have frequently been reported. However, the mechanism is still unclear. In...

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Bibliographic Details
Main Authors: Yida Zhang, Xiqing Bian, Jing Yang, Haiying Wu, Jian-Lin Wu, Na Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00275/full