Reduced GABAB receptor subunit expression and paired-pulse depression in a genetic model of absence seizures

Reduced GABAB receptor subunit expression and paired-pulse depression in a genetic model of absence seizures

Neocortical networks play a major role in the genesis of generalized spike-and-wave (SW) discharges associated with absence seizures in humans and in animal models, including genetically predisposed WAG/Rij rats. Here, we tested the hypothesis that alterations in GABAB receptors contribute to neocor...

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Bibliographic Details
Main Authors: D. Merlo, C. Mollinari, Y. Inaba, A. Cardinale, A.M. Rinaldi, M. D’Antuono, G. D’Arcangelo, V. Tancredi, D. Ragsdale, M. Avoli
Format: Article
Language:English
Published: Elsevier 2007-03-01
Series:Neurobiology of Disease
Subjects:
Absence seizures
GABAB receptor
Immunofluorescence
Paired-pulse depression
Real-Time PCR
WAG/Rij rats
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106002993

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http://www.sciencedirect.com/science/article/pii/S0969996106002993

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