Interleukin-1α expression precedes IL-1β after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues

<p>Abstract</p> <p>Background</p> <p>Cerebral ischemia is a devastating condition in which the outcome is heavily influenced by inflammatory processes, which can augment primary injury caused by reduced blood supply. The cytokines interleukin-1α (IL-1α) and IL-1β are ke...

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Bibliographic Details
Main Authors: Luheshi Nadia M, Kovács Krisztina J, Lopez-Castejon Gloria, Brough David, Denes Adam
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/8/1/186