Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis

Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis

Uveitis is characterized as a common cause of blindness worldwide. Aryl hydrocarbon receptor (AhR), a ligand-activated nuclear receptor, has been implicated to play a role in human uveitis, although the exact mechanisms remain poorly understood. The purpose of this study was to enhance our knowledge...

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Bibliographic Details
Main Authors: Yike Huang, Junchi He, Huaping Liang, Ke Hu, Shaoqiu Jiang, Lu Yang, Suyin Mei, Xiao Zhu, Jing Yu, Aize Kijlstra, Peizeng Yang, Shengping Hou
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
TCDD
aryl hydrocarbon receptor
experimental autoimmune uveitis
blood–retinal barrier
macrophage/microglia
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01713/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01713/full

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