The Prognostic Significance of Metabolic Response Heterogeneity in Metastatic Colorectal Cancer.

Tumoral heterogeneity is a major determinant of resistance in solid tumors. FDG-PET/CT can identify early during chemotherapy non-responsive lesions within the whole body tumor load. This prospective multicentric proof-of-concept study explores intra-individual metabolic response (mR) heterogeneity...

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Main Authors: Alain Hendlisz, Amelie Deleporte, Thierry Delaunoit, Raphaël Maréchal, Marc Peeters, Stéphane Holbrechts, Marc Van den Eynde, Ghislain Houbiers, Bertrand Filleul, Jean-Luc Van Laethem, Sarah Ceyssens, Anna-Maria Barbuto, Renaud Lhommel, Gauthier Demolin, Camilo Garcia, Hazem El Mansy, Lieveke Ameye, Michel Moreau, Thomas Guiot, Marianne Paesmans, Martine Piccart, Patrick Flamen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4589397?pdf=render