X-linked inhibitor of apoptosis (XIAP) – a critical death-resistance regulator and therapeutic target for personalized cancer therapy
Defects in apoptosis regulation are one main cause of cancer development and may result from overexpression of anti-apoptotic proteins such as Inhibitor of Apoptosis Proteins (IAPs). IAPs are cell death regulators that, among other functions, bind caspases and interfere with apoptotic signaling via...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2014-07-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00197/full |