Resistance to Novel Antiandrogen Therapies in Metastatic Castration-Resistant Prostate Cancer

Despite the introduction of novel therapies that maximally decrease androgen-receptor (AR) signaling activity, metastatic castration-resistant prostate cancer (mCRPC) remains a lethal disease. Even though abiraterone and enzalutamide represent breakthroughs in the treatment of mCRPC and have demonst...

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Bibliographic Details
Main Authors: Karim Boudadi, Emmanuel S. Antonarakis
Format: Article
Language:English
Published: SAGE Publishing 2016-01-01
Series:Clinical Medicine Insights: Oncology
Online Access:https://doi.org/10.4137/CMO.Ss34534