Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease
Iron-sulfur (Fe-S) clusters are ubiquitous cofactors composed of iron and inorganic sulfur. They are required for the function of proteins involved in a wide range of activities, including electron transport in respiratory chain complexes, regulatory sensing, photosynthesis and DNA repair. The prote...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2012-03-01
|
Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/5/2/155 |