Poly(NIPAM-co-MPS)-grafted multimodal porous silica nanoparticles as reverse thermoresponsive drug delivery system

Poly(NIPAM-co-MPS)-grafted multimodal porous silica nanoparticles as reverse thermoresponsive drug delivery system

Hybrid drug delivery systems (DDS) have been prepared by grafting poly(NIPAM-co-MPS) chains on multimodal porous silica nanoparticles having an inner mesoporous structure and an outer thin layer of micropores. The hybrid thermoresponsive DDS were fully characterized and loaded with a model drug. The...

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Bibliographic Details
Main Authors: Sushilkumar A. Jadhav, Valentina Brunella, Dominique Scalarone, Gloria Berlier
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Porous silica nanoparticles
Thermoresponsive polymer
Drug delivery system
Ibuprofen
Drug loading
Drug release profile
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087616302719

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http://www.sciencedirect.com/science/article/pii/S1818087616302719

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