Epigenetic Modifications of the PGC-1α Promoter during Exercise Induced Expression in Mice.

The transcriptional coactivator, PGC-1α, is known for its role in mitochondrial biogenesis. Although originally thought to exist as a single protein isoform, recent studies have identified additional promoters which produce multiple mRNA transcripts. One of these promoters (promoter B), approximatel...

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Bibliographic Details
Main Authors: Timothy L Lochmann, Ravindar R Thomas, James P Bennett, Shirley M Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4460005?pdf=render