Genomic Determinants Encode the Reactivity and Regioselectivity of Flavin-Dependent Halogenases in Bacterial Genomes and Metagenomes
Halogenases are playing an important role as tailoring enzymes in biosynthetic pathways. Flavin-dependent tryptophan halogenases (Trp-FDHs) are among the enzymes that have broad substrate scope and high selectivity.
Main Authors: | Jehyun Jeon, Jaehee Lee, Se-Min Jung, Jae Hong Shin, Woon Ju Song, Mina Rho |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2021-06-01
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Series: | mSystems |
Online Access: | https://journals.asm.org/doi/10.1128/mSystems.00053-21 |
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