Genomic Determinants Encode the Reactivity and Regioselectivity of Flavin-Dependent Halogenases in Bacterial Genomes and Metagenomes

Halogenases are playing an important role as tailoring enzymes in biosynthetic pathways. Flavin-dependent tryptophan halogenases (Trp-FDHs) are among the enzymes that have broad substrate scope and high selectivity.

Bibliographic Details
Main Authors: Jehyun Jeon, Jaehee Lee, Se-Min Jung, Jae Hong Shin, Woon Ju Song, Mina Rho
Format: Article
Language:English
Published: American Society for Microbiology 2021-06-01
Series:mSystems
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00053-21