Prospective randomized trial comparing efficacy and safety of intravenous and intra-articular tranexamic acid in total knee arthroplasty

Abstract Background Total knee arthroplasty (TKA) is associated with significant perioperative blood loss and postoperative allogenic blood transfusion. Tranexamic acid (TXA) reversibly blocks lysine binding sites on plasminogen molecules and inhibits plasmin formation. Comparisons of the efficacy a...

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Bibliographic Details
Main Authors: Moses Man-Lung Li, Jojo Yan-Yan Kwok, Kwong-Yin Chung, Kin-Wing Cheung, Kwok-Hing Chiu, Wai-Wang Chau, Kevin Ki-Wai Ho
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Knee Surgery & Related Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s43019-020-00079-8