Purification and Preliminary Crystallographic Analysis of a New Lys49-PLA2 from B. Jararacussu

Purification and Preliminary Crystallographic Analysis of a New Lys49-PLA2 from B. Jararacussu

BjVIII is a new myotoxic Lys49-PLA2 isolated from Bothrops jararacussu venom that exhibits atypical effects on human platelet aggregation. To better understand the mode of action of BjVIII, crystallographic studies were initiated. Two crystal forms were obtained, both containing two molecules in the...

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Bibliographic Details
Main Authors: Ricardo Aparicio, Marcos H. Toyama, Bruno R. F. Teixeira, Fábio H. R. Fagundes, Marcelo L. dos Santos
Format: Article
Language:English
Published: MDPI AG 2008-05-01
Series:International Journal of Molecular Sciences
Subjects:
Lys49-PLA2
Bothrops jararacussu
platelet aggregation
phospholipase crystallographic analysis
Online Access:http://www.mdpi.com/1422-0067/9/5/736/

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http://www.mdpi.com/1422-0067/9/5/736/

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