Analysis of substitution rates showed that TLR5 is evolving at different rates among mammalian groups

Analysis of substitution rates showed that TLR5 is evolving at different rates among mammalian groups

Abstract Background Toll-like receptors (TLRs) are the most widely studied innate immunity receptors responsible for recognition of invading pathogens. Among the TLR family, TLR5 is the only that senses and recognizes flagellin, the major protein of bacterial flagella. TLR5 has been reported to be u...

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Bibliographic Details
Main Authors: Ana Pinheiro, Ana Águeda-Pinto, José Melo-Ferreira, Fabiana Neves, Joana Abrantes, Pedro J. Esteves
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Evolutionary Biology
Subjects:
TLRs
Substitution rate
Relaxed selection
Evolution
Online Access:https://doi.org/10.1186/s12862-019-1547-4

Internet

https://doi.org/10.1186/s12862-019-1547-4

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