Evolutionary conservation and divergence of the human brain transcriptome

Abstract Background Mouse models have allowed for the direct interrogation of genetic effects on molecular, physiological, and behavioral brain phenotypes. However, it is unknown to what extent neurological or psychiatric traits may be human- or primate-specific and therefore which components can be...

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Bibliographic Details
Main Authors: William G. Pembroke, Christopher L. Hartl, Daniel H. Geschwind
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-020-02257-z