Epigenetic induction of tumor stemness via the lipopolysaccharide-TET3-HOXB2 signaling axis in esophageal squamous cell carcinoma

Epigenetic induction of tumor stemness via the lipopolysaccharide-TET3-HOXB2 signaling axis in esophageal squamous cell carcinoma

Abstract Background Esophageal squamous cell cancer (ESCC) is one kind of frequent digestive tumor. The inflammatory environment plays an important role in the tumorigenesis and development of ESCC. Cancer stem cells are a small group of tumor cells with stem cell characteristics, which can potentia...

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Bibliographic Details
Main Authors: Fengkai Xu, Zhonghe Liu, Ronghua Liu, Chunlai Lu, Lin Wang, Wei Mao, Qiaoliang Zhu, Huankai Shou, Kunpeng Zhang, Yin Li, Yiwei Chu, Jie Gu, Di Ge
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Cell Communication and Signaling
Subjects:
Lipopolysaccharide
Stemness
Esophageal squamous cell carcinoma
Ten-eleven-translocation (TET)
Homeobox B2 (HOXB2)
Online Access:https://doi.org/10.1186/s12964-020-0510-8

Internet

https://doi.org/10.1186/s12964-020-0510-8

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